Why is wellbutrin contraindicated for eating disorders

The patient began taking mg of bupropion XR daily, which she gradually increased to —mg per day. Despite experiencing 2 grand-mal seizures after 6 months of abuse, the patient increased her bupropion dose to as much as During her most frequent abuse period, the patient reported experiencing headaches, tachycardia, anxiety, and insomnia. Following an attempted suicide 1 year after her bupropion XR abuse began, the patient received treatment for pancreatitis, as well as psychiatric and eating disorder management over a 3 month period.

Is it just the weightloss side effect or does it make them worse? Should I be on something else? Female, mid-twenties. It's an appetite suppressant. When I was on wellbutrin I had to remind myself to eat or it wouldn't occur to me until I was about to pass out.

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Little late here, but During that time I suffered two seizures one during a hike, one after a spin class —both times when I had not eaten much that day. Stopped Wellbutrin and haven't suffered a seizure since.

It is a little late but I decided to publish your post because of the significance for the following reasons: 1. Wellbutrin bupropion is one the the most popular antidepressants currently in use. It is being prescribed to people with active eating disorders and that is a contraindication. Your experience is consistent with the FDA contraindication cited above. I have not received an adequate response on the issue of use in women with a history of eating disorders that are no longer active from any of my inquiries.

Even in persons without an eating disorder bupropion has a higher incidence of seizures than other antidepressants. It sounds like you did not sustain any long term complications. It is good to hear that you stopped the bupropion and were able to identify it as the causal agent. I am writing to confirm that the contraindication warning is useful, from my personal experience.

I am a 59 year old female who suffered long term depression from complicated grief. I had a 13 year history of bulimia, from age 13 to Lack of motivation and dystonia was impairing my professional life. Since increased dopamine is helpful to increasing motivation, I utilized both natural and pharmaceutical methods.

Regular aerobic activity, novel experience, and foods containing precursors have been helpful. However ,I noticed the greatest improvement within 1 week of taking twice daily doses of mg SR Bupropion. I also noticed small tremors twitching in my fingers.

I am fearful of a seizure, as I do not want to risk any incidents that may lead to memory loss, considering my age and family history. Upon stopping the Bupropion for two days, the twitching decreases or goes away. This correlates with the half-life information in the medication pamphlet. However, I also notice a return of depression.

It is difficult for me to weigh the risks and benefits, as I do not know if I risk a seizure, not would I want any permanent dyskinesia. I also use Bupropion with great success for binge eating disorder BED when someone is not interested in Vyvanse, a stimulant medication FDA approved for the condition. The stimulant effects of Bupropion have been studied because it has structural similarities to amphetamine, therefore it has been a notable option for the treatment of ADHD.

Studies have shown that although structurally similar to amphetamines, comparable abuse potential though has not been demonstrated. In addition to our probable overconcern for the association of Bupropion and seizures, the role in which this medication plays in the treatment of eating disorder is undoubtedly underestimated.

This is commonly treated with a stimulant medication. Another commonly diagnosed condition is major depressive disorder or MDD. From personal experience these medications rarely help patients with eating disorders with most requesting a continuous increase in dose or addition of another medication due to failed symptom improvement.

Those familiar with eating disorders patients are aware that there is a very strong addiction component. I use naltrexone in patients with polydipsia and dissociative disorder frequently with immense success. Maybe pairing Bupropion and Naltrexone to help with temporarily treating eating disorders is something that should be considered? After discharge from residential facilities the slew of medications an individual is prescribed is illogical. The customary cocktail of choice appears to be a SSRI, sometimes with an SNRI, atypical antipsychotic at bedtime, and antiepileptic for mood dysfunction.

My patients who do take Bupropion are usually o a one drug regimen, forgoing the mental health cocktail.